Category: <span>Volume 01 Number 01</span>

Seasonal Variation in Heavy Metal Distribution in the Sediments of Selected Dams in Nasarawa State, Nigeria

Introduction  Monitoring the concentration of heavy metals in sediment is important since knowledge of trace metals level in surface waters gives vital information regarding their sources, distribution and degree of pollution. This is for the fact that sedimentation has been regarded as one of the most important fluxes in aquatic …

Synthesis of Three Progesterone Derivatives. Theoretical Evaluation of its Interact with Androgen Receptor and Cytochrome P450 17A1 Enzyme

Introduction Prostate cancer is one of the main health problems worldwide [1,2]; it is important to mention that several drugs have been used for the treatment of this clinical pathology such as flutamide [3], apalutamide [4], bicalutamide [5], abiraterone [6], leuprolide [7], gosereline [8] and others; however, some of these …

Fixed Bed Column Study of Hazardous Rose Bengal Dye from Wastewater Using Waste Material De–Oiled Soya

Introduction Rose Bengal [IUPAC name 4,5,6,7-Tetrachloro-3,6’-dihydroxy-2,4,5,7-Tetraiodospiro (isobenzofuran-1 (3H), 9-(9H) xanthen)-3-one] is popularly known as Acid Red 94, Food Red Dye 105, Bengal Rose or Red No.105 (Fig. 1). It is a well known fluorescein class of halogen containing highly water soluble, anionic dye.  It is widely used in liver function …

Bioaccumulation and Distribution of Cadmium and Zinc in Jute Mallow (Corchorus olitorius)

Introduction Jute Mallow (Corchorus olitorius) is a popular leafy vegetable that is cultivated in the dry, semi-arid and humid regions of Africa primarily for its nutritional value1. It is a rich source of iron [and therefore recommended for pregnant women and nursing mother2, protein, calcium, thiamin, riboflavin, niacin, folate, and …

Multiply-Functionalized BC2N Nanotubes through [2+1] cycloaddition with carbenes: Intramolecular Hydrogen Bondings

Introduction Because of their extraordinary properties, single-walled nanotubes (SWNTs) can be considered as attractive candidates in diverse nanotechnological applications, such as molecular devices, molecular tanks, (bio) sensors, drug delivery, and many others [1-12]. It has been demonstrated that SWNTs can interact with different classes of compounds, and the formation of …

Stability-Indicating RP-HPLC Method Development for Determination and Estimation of Valacyclovir in Raw and Tablet Formulation.

Introduction Valacyclovir hydrochloride is L -valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H -purin-9-yl)methoxy] ethyl ester, monohydrochloride [1]. It is an antiviral agent, which is used in the treatment of herpes zoster and herpes simplex virus [1]. Literature review shows minimal methods has been developed and reported for Valacyclovir estimation in biological fluids and there are …

Chemical Speciation and Risk Implications of Some Heavy Metals in Sediment Profiles of Urban Stream Stretches, Yenagoa City, Bayelsa State, Nigeria

Introduction The indiscriminate dumping of degradable or non-degradable wastes into urban stream stretches and rivers has been considered one of the major causes of the unprecedented mush-rooming of heavy metals and their speciation and the results are effect on ecosystems and human health risk implications globally. Sediments are considered to …