Stability-Indicating RP-HPLC Method Development for Determination and Estimation of Valacyclovir in Raw and Tablet Formulation.
Introduction Valacyclovir hydrochloride is L -valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H -purin-9-yl)methoxy] ethyl ester, monohydrochloride [1]. It is an antiviral agent, which is used in the treatment of herpes zoster and herpes simplex virus [1]. Literature review shows minimal methods has been developed and reported for Valacyclovir estimation in biological fluids and there are …