Metabolic Stability Evaluation of a Hydrazone-Sulfonate Derivative: N′-[(4-Chlorophenyl)methylidene)]-4-[(4-methylphenyl)sulfonyloxy]benzohydrazide
1. Introduction Evaluating the metabolic profile of drug candidates is one of the most vital stages in drug discovery and development processes [1]. In the past, metabolic assessments were seldom conducted before the early clinical phases. Consequently, poor metabolism and inadequate pharmacokinetic parameters were among the leading causes of drug development …