Category: Volume 04 Number 02

Introduction Erythromycin, a macrolide antibiotic produced by Streptomyces erythraea, functions as an antibacterial agent effective against various bacterial infections. Chemically, Erythromycin is characterized as 6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione (C37H67NO13, molecular weight 733.92 g/mol). Its mechanism of action involves inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby inhibiting peptidyl …

Introduction Malaria remains one of the world’s deadliest infectious diseases. It is caused by protozoa of the genus Plasmodium and transmitted to humans through the bite of infected Anopheles mosquitoes. The parasites first target the liver before invading red blood cells, leading to symptoms like fever, chills, and fatigue. Among …

1.1. DIABETES: Diabetes is a disorder where the blood glucose (sugar) level was higher than normal Blood glucose (sugar) level is known as Hyperglycemia. Blood glucose levels are normally controlled by the hormone called insulin which is produced by beta cells of Langerhans in the pancreas (a gland which lies …

Introduction The course of human history has been intricately intertwined with the evolution and utilization of materials, with each advancement shaping cultures and contributing significantly to the growth of civilizations. In recent decades, the exploration of materials at the micro and nano scales has opened up a vast research arena, …

Halogenated aromatic compounds are of considerable commercial importance in organic synthesis. These compounds are potential disinfectant1, antiseptic2 and Fungicides3 and key precursors in the synthesis of organometallic regents4-7 and coupling reactions8. Halogenation of aromatic substrates are electrophilic aromatic substitution reaction9-10. Among halogenation of aromatic substrates, bromination is the fastest followed …