The synthesis, structural elucidation, and crystallographic analysis of a novel hydrazone-based coordination polymer of zinc are presented. The compound was synthesized via the reaction of isonicotinoylhydrazide with an appropriate aldehyde derivative, followed by complexation with a zinc(II) salt under solvothermal conditions. Single-crystal X-ray diffraction studies revealed that the complex crystallizes in the monoclinic crystal system with the P2₁/n space group. The asymmetric unit comprises one discrete coordination polymeric entity, and the unit cell accommodates four such molecules. The polymeric framework is stabilized by a network of weak intermolecular supramolecular interactions, including hydrogen bonding and π–π stacking, which govern the three-dimensional packing architecture. This study highlights the potential of hydrazone ligands in constructing metal-organic frameworks with defined geometries and packing arrangements, offering insights into their structural chemistry and possible functional applications in coordination-driven materials.