Abstract for Post: Oral Administration of Moringa oleifera Leaf Ethanol Extract Attenuates IL-6 and TNF-α Levels in Obese Wistar Rats

Author(s): S. Praveen & Priya Das
Affiliation: Dr. Ambedkar Institute of Management Studies and Research, Nagpur.
Corresponding Email: priyadas_pharma@outlook.com

Obesity-related chronic inflammation raises IL-6 and TNF-α levels. This study evaluated the effect of orally administered ethanol extract of Moringa oleifera leaves on these inflammatory markers in obese Wistar rats. Fifteen rats were divided into three groups: normal control, obese control, and treatment. After obesity induction via a high-fat diet, the treatment group received 300 mg/kg BW of Moringa oleifera extract for four weeks. Results showed significant reductions in IL-6 and TNF-α levels in the treatment group, indicating the extract’s anti-inflammatory potential.